UK drug shortages list
The Clinigen Direct UK drug shortages platform is for the support of UK healthcare professionals only. It provides a regularly updated, fully comprehensive UK drug shortage list and highlights the existing alternative available. By reviewing the content below you are confirming you are a UK healthcare professional.
Although Clinigen Direct has performed an alternative assessment of these products, please note, it is the prescriber’s responsibility to ensure that the product is suitable for their patient. Due to the below lines not being general stock lines we are unable to cancel any purchase orders once the order has been placed.
| In shortage | Alternative | Form and pack size | Start Date | Status | |
|---|---|---|---|---|---|
| aprepitant | aprepitant (125mg and 80mg) | Capsule, Hard 1 x 1 + 1 x 2 | January 2025 | Current | Request medicine |
| peginterferon alfa-2 | peginterferon alfa-2 (180mcg (0.36mg/ml)) | Solution For Injection (Pre-Filled Syringe) 1 x 0.5ml + 1 injection needle | November 2024 | Current | Request medicine |
| peginterferon alfa-2a | peginterferon alfa-2a (90mcg/0.5ml) | Solution For Injection (Pre-Filled Syringe) 1 x 0.5 ml | November 2024 | Current | Request medicine |
| peginterferon alfa-2 | peginterferon alfa-2 (135mcg (0.27mg/ml)) | Solution For Injection (Pre-Filled Syringe) 1 x 0.5ml + 1 injection needle | November 2024 | Current | Request medicine |
| lumefantrinum+ artemetherum | lumefantrinum (120 MG)+ artemetherum (20 MG) | Tablet 1 x 24 | October 2024 | Current | Request medicine |
| calcium folinate (leucovorin calcium/folinic acid) | calcium folinate (leucovorin calcium/folinic acid) (350 MG) | Lyophilized Powder for Injection 1 x 1 | October 2024 | Current | Request medicine |
| folinic acid (as calcium folinate) | folinic acid (as calcium folinate) (300mg/30ml (10mg/ml)) | Solution For Injection (Vial) 1 x 30ml | October 2024 | Current | Request medicine |
| folinic acid (as calcium folinate) | folinic acid (as calcium folinate) (500mg (10mg/ml)) | Solution For Infusion/Injection (Vial) 1 x 50ml | October 2024 | Current | Request medicine |
| calcium folinate (leucovorin calcium/folinic acid) | calcium folinate (leucovorin calcium/folinic acid) (350mg/17.5ml (20mg/ml)) | Injection powder Lyophilized Powder for solution 1 x 35ml | October 2024 | Current | Request medicine |
| indocyanine green | indocyanine green (25 MG) | Injection 1 x 1 | October 2024 | Current | Request medicine |
| pancreatin (amylase + lipase + protease) | pancreatin (amylase + lipase + protease) (60.12mg/100mg (3600 IU + 5000 IU + 200 IU)) | Gastro-Resistant Granule (Micro Pellet) 1 x 20g | October 2024 | Current | Request medicine |
| thiamine hydrochloride | thiamine hydrochloride (100 mg/ml) | Solution for Injection 6 x 1 ml | August 2024 | Current | Request medicine |
| Desmopressin Acetate | Desmopressin Acetate (0.004 MG/ML) | Solution For Injection (Ampoule) 10 x 1 ML | July 2024 | Current | Request medicine |
| ipratropium bromide | ipratropium bromide (0.25 mg/ml (500mcg/2ml)) | Solution For Nebulisation (Single-Dose) 20 x 2 ml | July 2024 | Current | Request medicine |
| ipratropium bromide | ipratropium bromide (0.25 mg/ml (250mcg/ml)) | Solution For Nebulisation (Single-Dose) 20 x 1 ml | July 2024 | Current | Request medicine |
| cisplatin | cisplatin (1 MG/ML) | Solution For Injection (Vial) 1 x 100 ml | July 2024 | Current | Request medicine |
| Ipratropium Bromide | Ipratropium Bromide (500mcg/2.5ml (0.02%)) | Inhalation Solution 25 x 2.5ML | July 2024 | Current | Request medicine |
| lipase + amylase + protease | lipase + amylase + protease (10000 IU + 8000 IU + 600 IU) | Gastro-Resistant Hard Capsule 1 x 100 | June 2024 | Current | Request medicine |
| lipase + amylase + protease | lipase + amylase + protease (25000 IU + 18000 IU + 1000 IU) | Gastro-Resistant Hard Capsule 1 x 100 | June 2024 | Current | Request medicine |
| porcine pancreas powder+ with amylase/lipase/protease activity | porcine pancreas powder (25000 PhEur units)+ with amylase/lipase/protease activity () | Gastro-resistant Capsule 1 x 200 | June 2024 | Current | Request medicine |
| disopyramide | disopyramide (100 MG) | Hard Capsule 1 x 84 | June 2024 | Current | Request medicine |
| aciclovir | aciclovir (250 mg) | Powder for Solution for Infusion 10 x 10 ml | May 2024 | Current | Request medicine |
| aciclovir | aciclovir (25 MG/ML) | Concentrate For Solution For Infusion (Vial) 5 x 10ml | April 2024 | Current | Request medicine |
| vinblastine sulfate | vinblastine sulfate (1 MG/ML) | Solution For Injection (Vial) 1 x 10 ml | April 2024 | Current | Request medicine |
| idarubicin | idarubicin (1 MG/ML) | Solution For Injection (Vial) 1 x 10 ml | April 2024 | Current | Request medicine |
| guanfacine hydrochloride | guanfacine hydrochloride (1 MG) | Modified-Release Tablet 1 x 28 | March 2024 | Current | Request medicine |
| guanfacine hydrochloride | guanfacine hydrochloride (4 MG) | Modified-Release Tablet 1 x 28 | March 2024 | Current | Request medicine |
| idarubicin hydrochloride | idarubicin hydrochloride (1 MG/ML) | Solution For Injection 1 x 5 ml | March 2024 | Current | Request medicine |
| racemic phytomenadione | racemic phytomenadione (10mg) | Tablet 1 x 30 | March 2024 | Current | Request medicine |
| salbutamol sulphate | salbutamol sulphate (0.2% (2 MG/ML)) | Solution For Oral Inhalation 20 x 2.5 ml | March 2024 | Current | Request medicine |
| salbutamol sulphate | salbutamol sulphate (0.1% (1 MG/ML)) | Solution For Oral Inhalation 20 x 2.5 ml | March 2024 | Current | Request medicine |
| meglumine diatrizoate+ sodium diatrizoate | meglumine diatrizoate (660 MG/ML)+ sodium diatrizoate (100 MG/ML) | Oral Solution 1 x 100 ml | March 2024 | Current | Request medicine |
| sulfamethoxazole+ trimethoprim | sulfamethoxazole (200mg)+ trimethoprim (40mg) | Oral Suspension 100ml | February 2024 | Current | Request medicine |
| reslizumab | reslizumab (10 mg/ml) | Concentrate for Solution for Infusion 2 x 2.5ml | February 2024 | Current | Request medicine |
| reslizumab | reslizumab (10 mg/ml) | Concentrate for Solution for Infusion 2 x 10ml | February 2024 | Current | Request medicine |
| pamidronate disodium | pamidronate disodium (30 mg/10 ml) | Solution for Injection 1x10ml | February 2024 | Current | Request medicine |
| Ergocalciferol | Ergocalciferol (7.5 MG/ML (300,000 IU)) | Solution For Injection (Ampoule) 5 x 1 ml | January 2024 | Current | Request medicine |
| pamidronate disodium | pamidronate disodium (90 MG) | Powder and Solvent for Solution for Infusion 1x(1+1) | January 2024 | Current | Request medicine |
| pamidronate disodium | pamidronate disodium (30 mg/ 10ml) | Concentrate for Solution for Infusion 1 x 10ml | January 2024 | Current | Request medicine |
| acetylcholine chloride | acetylcholine chloride (20 MG) | Powder And Solvent For Suspension For Injection (Vial) 1 x 1 | January 2024 | Current | Request medicine |
| propantheline bromide | propantheline bromide (15 mg) | Film-coated Tablet 1 x 100 | January 2024 | Current | Request medicine |
| eptifibatide | eptifibatide (2 mg/ml) | Solution For Injection (Vial) 1 x 10 ml | November 2023 | Current | Request medicine |
| acetylcholine chloride | acetylcholine chloride (20 mg) | Powder and Solvent for Solution for Injection for Intraocular use 1 x (6 + 6) | November 2023 | Current | Request medicine |
| carboplatin | carboplatin (10mg/ml) | Solution for Infusion 1 x 60ml | July 2023 | Current | Request medicine |
| cisplatin | cisplatin (1mg/mL) | Concentrate for Solution for Infusion 1 x 50 ml | July 2023 | Current | Request medicine |
| potassium iodide | potassium iodide (65mg) | Tablet 1 x 10 | June 2023 | Current | Request medicine |
| dextromethorphan hydrobromide | dextromethorphan hydrobromide (30 mg/5ml) | Extended Release Oral Suspension 1 x 89 ml | June 2023 | Current | Request medicine |
| terizidone | terizidone (250 mg) | Capsule, Hard 1 x 50 | November 2022 | Current | Request medicine |
| tenecteplase | tenecteplase (50 mg (10,000 U)) | Lyophilisate and Solvent for Solution for Injection 1 x (1+1+1) | July 2022 | Current | Request medicine |
| epinephrine+ lidocaine hydrochloride | epinephrine (1:200 000 (5 mcg/ml))+ lidocaine hydrochloride (2% (20 mg/ml)) | Solution for Injection 10 x 20 ml | June 2022 | Current | Request medicine |
| sodium thiosulfate | sodium thiosulfate (250 mg/ml (25%)) | Solution for Injection 1 x 50mL | November 2021 | Current | Request medicine |
| lidocaine hydrochloride+ adrenaline hydrochloride | lidocaine hydrochloride (1% (10mg/ml))+ adrenaline hydrochloride (1:100 000 (10 mcg/ml)) | Solution for Injection 1 x 20ml | September 2021 | Current | Request medicine |
| sodium nitrite | sodium nitrite (30mg/ml) | Solution for Injection 1 x 10 ml | September 2021 | Current | Request medicine |
| sodium thiosulfate | sodium thiosulfate (25%) | Injection 10 x 100 ml | September 2021 | Current | Request medicine |
| bleomycin sulfate | bleomycin sulfate (15 units (15,000 iu)) | Lyophilisate for Solution for Injection 1 x 1 | September 2020 | Current | Request medicine |
| bleomycin sulfate | bleomycin sulfate (15 units (15,000 iu)) | Lyophilisate for Solution for Injection 1 x 1 | April 2020 | Current | Request medicine |
| pyridostigmine bromide | pyridostigmine bromide (60 mg) | Tablet 1 x 20 | January 0001 | Current | Request medicine |